Company Position Nationality
Kansai technology Licensing Adviser Adviser Albanie
Session
What is the best background for an academic spin-off CEO?

 

NAME                                                 CURRENT POSITION TITLE

Daisuke SUGIYAMA             Professor, Department of Research and Development of Next Generation Medicine, Faculty of Medical Sciences, Kyushu University

 

 

 

EDUCATION (begin with high school education.)

                                                                      YEAR

INSTITUTION AND LOCATION                                                   DEGREE        CONFERRED      FIELD OF STUDY

 

Kanto-gakuin Mutsuura high school(Yokohama)

 

Gunma University, School of Medicine            MD        1996          Medicine

 

Graduate School of Medicine,

The University of Tokyo                         PhD       2003          Medicine

 

Professional Experience

PRINCIPAL POSITIONS HELD:

1996-1997 The 3rd department of Internal Medicine, Gunma Medical Doctor  
1997-1997 Kokuritsu Takasaki Hospital Medical Doctor  
1997-1998 Saiseikai Maebashi Hospital Medical Doctor  
1998-1999 Saito Kinen Hospital Medical Doctor  
1999-2003 Division of Molecular and Developmental Biology, Department of Basic Medical Sciences, The Institute of Medical Science, The University of Tokyo.

Work supervised by Professor Ken-ichi Arai and Associate professor Kohichiro Tsuji.

Graduate student  
2002-2004 Developmental Biology Laboratory, University Pierre and Marie Curie (Paris 6). Work supervised by CR1 Thierry Jaffredo. French Government Scholar  
2004-2006 Department of Biochemistry, Dartmouth Medical School. Work supervised by Professor Nancy Speck. Postdoctoral Research Fellow  
2006 Department of Cell Differentiation, Keio University School of Medicine. Work supervised by Professor Toshio Suda. Research Assistant Professor  
2006-2011 SSP Department of Hematopoietic Stem Cells, Kyushu University Faculty of Medical Sciences Associate Professor  
2011-2012 Div. of Hematopoietic Stem Cells, Dep. of Advanced Medical Initiatives, Kyushu University Faculty of Medical Sciences Associate Professor  
2012-2013

 

Network Coordination Unit, Center for clinical and Translational Research, Kyushu Univ. Hospital Associate Professor  
2013-2014 Department of Research and Development of Next Generation Medicine, Kyushu University Faculty of Medical Sciences Associate Professor  
2014-2016 Department of Clinical Study, Center for Advanced Medical Innovation, Kyushu University Professor

(Department Head)

 

 
Apr. 2016-present Department of Research and Development of Next

Generation Medicine, Faculty of Medical Sciences,

Kyushu University

Professor  

                      

 

OTHER POSITIONS HELD CONCURRENTLY:

2002-2004 Developmental Biology Laboratory in University Pierre and Marie Curie (Paris 6). Work supervised by CR1 Thierry Jaffredo. French Government Scholar
2004-2006 Department of Biochemistry in Dartmouth Medical School. Work supervised by Professor Nancy Speck. Postdoctoral Research Fellow supported by JSPS (Japanese Society for the Promotion of Science)
2008-2011 Science Lustre CO., LTD CEO
2012 Junshin Gakuen University Part-time Lecturer
2013 KANSAI TLO CO., LTD

(Technology Licensing Organization)

Adviser
2014 Junshin Gakuen University Visiting Professor

 

Honors and Memberships:

Honors

2002: 1, Travel Award by Mitsubishi Pharma Research Foundation.
2, French Government Scholarship.
2003: 1, Travel Award by Mitsukoshi Health And Welfare Foundation.
2, Travel Award by Sankyo Foundation of Life Science.
3, Travel Award by SUMITOMO Life Social Welfare Services Foundation.
4, Inoue Foundation for Science, International Scientific Exchange Programs, Assistance for participation in scientific meetings abroad.
2004: 1, Postdoctoral Fellowship for Research Abroad by JSPS (Japan Society for the Promotion of Science).
2006: 1, Research award by Naito Foundation.
2007: 1, Research award by Senshin-Iyaku Foundation
2008: 1, Research award by Nagao-Takeshi memorial foundation.
2, Research award by Sankyo-pharmaceutical foundation.
3, Research award for invitation of foreign scientists by Inoue Foundation.
2008: 1, Research award by Japan Leukemia Foundation.
2, SAKURA program to exchange between Japan and France by JSPS.
3, Research award by Naito Foundation.
2009: 1, Bilateral grant to exchange between England and Japan by JSPS.
2, Research award for invitation of foreign scientists by Nakajima international Foundation.
2010 1, Biolegend Special Award.
2011 1, Research award by Japan Leukemia Foundation.
2012

 

 

 

2013

 1, 2, 3, 4, 1, Research award by Kanae Foundation For the Promotion of Medical Science

The 27th Research Exchange award by The Ichiro Kanehara Foundation

Research award by The Ichiro Kanehara Foundation

Joint Research award by Science Lustre

PhRMA Researcher program by The Maureen and Mike Mansfield Foundation

 

Memberships

1996- present The Japanese Society of Internal Medicine
1996- present Japanese Society of Hematology
2005- present American Society of Hematology
2010- present Physiological Society of Japan
2010- present American Society of Physiology
2010- present FANTOM5 project
2011-present Japanese Society of Laboratory Medicine
2012-present

2012-present

International Society for Stem Cell Research

Japan Society of Clinical Trials and Research

2013-present                                 Society of Clinical Research Association

2014-present                                 The Japanese Society of Clinical Pharmacology and Therapeutics

2014-present                                The Japanese Society for Regenerative Medicine, authorized as Board Certified Member from Jan. 1, 2016 to Dec. 31, 2018

 

Licensure and Special Skills

1996.04 Medical licensure

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Bibliography

(1)Original Articles

1 Prospects for Harmonizing Regulatory Science Programs in Europe, Japan, and the United States to Advance Regenerative Medicine.  Milne CP, Mittra J, Kojima N, Sugiyama D, Awatin J, Simmons G. Therapeutic Innovation & Regulatory Science. 2016,in press
2 DBA Lectin Binds to Highly Proliferative Mouse Erythroleukemic Cells. Swain A, KulkeawK, Tanaka Y, Nakanishi Y, Shirasawa S, Sugiyama D. Anticancer Research. 2016, 36(7):3625-33.
3 Aryl Hydrocarbon Receptor Antagonist StemRegenin 1 promotes the expansion of human promyelocytic leukemia cell line, NB4. Koide R, Kulkeaw K, Tanaka Y, Swain A, Nakanishi Y, Sugiyama D. Anticancer Research, 2016, 36(7):3635-3643.
4 Embryonic intra-aortic clusters undergo myeloid differentiation mediated by mesonephros-derived CSF1 in mouse. Sasaki T,Tanaka Y,Kulkeaw K,Yumine A,Tan Keai-Sinn,Nishinakamura R,Ishida J,Fukamizu A,Sugiyama D. Stem Cell Reviews and Reports. 2016,in press
5 Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia

Collet G, Szade K, Nowak W, Klimkiewicz K, El Hafny-Rahbi B, Szczepanek K, Sugiyama D, Weglarczyk K, Foucault-Collet A, Guichard A, Mazan A, Nadim M, Fasani F, Lamerant-Fayel N, Grillon C, Petoud S, Beloeil JC, Jozkowicz A, Dulak J, Kieda C.

Cancer Letters           2016 Jan,370(2):345-57

6 Embryonic hematopoietic progenitors reside in muscle before bone marrow hematopoiesis.

Tanaka Y, Inoue-Yokoo T, Kulkeaw K, Yanagi-Mizuochi C, Shirasawa S, Nakanishi Y and Sugiyama D.

PLoS One,2015 Sep,10(9):e0138621

7 Apoptosis-inducing Factor, Mitochondrion-associated 2, Regulates Klf1 in a Mouse Erythroleukemia Cell Line.

Kojima N, Tanaka Y, Kulkeaw K, Nakanishi Y, Shirasawa S, Sugiyama D.

Anticancer Res,2015 Aug, 35(8):4493-9

8 Aloe vera Extract Suppresses Proliferation of Neuroblastoma Cells In Vitro. Yonehara A, Tanaka Y, Kulkeaw K, Era T, Nakanishi Y, Sugiyama D.

Anticancer Res,2015 Aug,35(8):4479-85

9 Ribosomal protein L11- and retinol dehydrogenase 11-induced erythroid proliferation without erythropoietin in UT-7/Epo erythroleukemic cells.

Kummalue T, Inoue T, Miura Y, Narusawa M, Inoue H, Komatsu N, Wanachiwanawin W, Sugiyama D, Tani K.

Exp Hematol,2015 May,43(5):414-423

10 Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos.

Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D.

Biol Open,2015 Apr,4(5):596-607

11 Gene regulation. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Arner E, Daub CO, Vitting-Seerup K, Andersson R, Lilje B,Sugiyama D. et al.

Science          2015 Feb,347(6225):1010-4

12 Intrinsic and extrinsic regulation of mammalian hematopoiesis in the fetal liver.            Swain A, Inoue T, Tan KS, Nakanishi Y, Sugiyama D.         HISTOLOGY AND HISTOPATHOLOGY    2014 Sep        29(9):1077-82
13 Dok2 likely down-regulates Klf1 in mouse erythroleukemia cells.

Tanaka Y, Kulkeaw K, Inoue T, Tan KS, Nakanishi Y, Shirasawa S, Sugiyama D.

Anticancer Res,2014 Aug,34(8):4561-7

14 Multicolor analysis of cell surface marker of human leukemia cell lines using flow cytometry.

Inoue T, Swain A, Nakanishi Y, Sugiyama D.

Anticancer Res,2014 Aug,34(8):4539-50.

15 Herbal drug ninjin’yoeito accelerates myelopoiesis but not erythropoiesis in vitro.

Inoue T, Kulkeaw K, Muennu K, Tanaka Y, Nakanishi Y, Sugiyama D.

Genes Cells,2014 May,19(5):432-40

16 A promoter-level mammalian expression atlas.

FANTOM Consortium and the RIKEN PMI and CLST (DGT), Forrest AR, Sugiyama D.

Nature,2014 Mar,507(7493):462-70

17 An atlas of active enhancers across human cell types and tissues.

Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Sugiyama D. et al.

Nature,2014 Mar,507(7493):455-461

18 Hemogenic endothelium: a vessel for blood production.

Antas VI, Al-Drees MA, Prudence AJ, Sugiyama D, Fraser ST.

Int J Biochem Cell Biol          ,2013 Mar,45(3):692-5

19 TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts.

Sugiyama D, Kulkeaw K, Mizuochi C.

Mech Dev,2013 Feb,130(2-3):195-206

20 Isolation of embryonic hematopoietic niche cells by flow cytometry and laser capture microdissection.

Sugiyama D, Sasaki T.

Methods Mol Biol,2013,1035:57-65

21 Ectopic expression of Hmgn2 antagonizes mouse erythroid differentiation in vitro.

Kulkeaw K, Inoue T, Mizuochi C, Horio Y, Ishihama Y, Sugiyama D.

Cell Biol Int,2012 Feb,36(2):195-202

22 Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.

Mizuochi C, Fraser ST, Biasch K, Horio Y, Kikushige Y, Tani K, Akashi K, Tavian M, Sugiyama D.

PLoS One,2012,7(4):e35763

23 Variation in mesodermal and hematopoietic potential of adult skin-derived induced pluripotent stem cell lines in mice.

Inoue T, Kulkeaw K, Okayama S, Tani K, Sugiyama D.

Stem Cell Rev,2011 Nov,7(4):958-68

24 Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production.

Sugiyama D, Kulkeaw K, Mizuochi C, Horio Y, Okayama S.

Biochem Biophys Res Commun,2011 Jul ,410(2):301-6

25 Cold exposure down-regulates zebrafish pigmentation.

Kulkeaw K, Ishitani T, Kanemaru T, Ivanovski O, Nakagawa M, Mizuochi C, Horio Y, Sugiyama D.

Genes Cells,2011 Apr,16(4):358-67

26 APOA-1 is a novel marker of erythroid cell maturation from hematopoietic stem cells in mice and humans.

Inoue T, Sugiyama D, Kurita R, Oikawa T, Kulkeaw K, Kawano H, Miura Y, Okada M, Suehiro Y, Takahashi A, Marumoto T, Inoue H, Komatsu N, Tani K.

Stem Cell Rev,2011 Mar,7(1):43-52

27 Embryonic regulation of the mouse hematopoietic niche.

Sugiyama D, Inoue-Yokoo T, Fraser ST, Kulkeaw K, Mizuochi C, Horio Y.ScientificWorldJournal,2011,11:1770-80

28 Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse.

Sasaki T, Mizuochi C, Horio Y, Nakao K, Akashi K, Sugiyama D.

Development,2010 Dec,137(23):3941-52

29 Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse.

Sasaki T, Mizuochi C, Horio Y, Nakao K, Akashi K, Sugiyama D.

Development,2010 Dec,137(23):3941-52

30 Variation in hematopoietic potential of induced pluripotent stem cell lines.

Kulkeaw K, Horio Y, Mizuochi C, Ogawa M, Sugiyama D.

Stem Cell Rev,2010 Sep,6(3):381-9

31 Cold exposure down-regulates zebrafish hematopoiesis.

Kulkeaw K, Ishitani T, Kanemaru T, Fucharoen S, Sugiyama D.

Biochem Biophys Res Commun,2010 Apr,394(4):859-64

32 Characterization of kidney marrow in zebrafish (Danio rerio) by using a new surgical technique.

Ivanovski O, Kulkeaw K, Nakagawa M, Sasaki T, Mizuochi Ch, Horio Y, Ishitani T, Sugiyama D.

Prilozi,2009 Dec,30(2):71-80

33 Application of whole mouse embryo culture system on stem cell research.

Kulkeaw K, Mizuochi C, Horio Y, Osumi N, Tsuji K, Sugiyama D.

Stem Cell Rev,2009 Jun        5, (2):175-80

34 Application of whole mouse embryo culture system on stem cell research.

Kulkeaw K, Mizuochi C, Horio Y, Osumi N, Tsuji K, Sugiyama D.

Stem Cell Rev,2009 Jun,       5(2):175-80

35 B cell potential can be obtained from pre-circulatory yolk sac, but with low frequency.

Sugiyama D, Ogawa M, Nakao K, Osumi N, Nishikawa S, Nishikawa S, Arai K, Nakahata T, Tsuji K.

Dev Biol,2007 Jan,301(1):53-61

36 T-lymphoid, megakaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage.

Talebian L, Li Z, Guo Y, Gaudet J, Speck ME, Sugiyama D, Kaur P, Pear WS, Maillard I, Speck NA.

Blood,2007 Jan,109(1):11-21

37 The allantois and chorion, when isolated before circulation or chorio-allantoic fusion, have hematopoietic potential.

Zeigler BM, Sugiyama D, Chen M, Guo Y, Downs KM, Speck NA.

Development,2006 Nov,133(21):4183-92

38 The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO’s activity.

Liu Y, Cheney MD, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH.       Cancer

Cell,2006 Apr,9(4):249-60

39 Widespread lipoplex-mediated gene transfer to vascular endothelial cells and hemangioblasts in the vertebrate embryo.

Boll?rot K, Sugiyama D, Escriou V, Gautier R, Tozer S, Scherman D, Jaffredo T.

Dev Dyn.,2006 Jan,235(1):105-14

40 Definitive hematopoiesis from acetyl LDL incorporating endothelial cells in the mouse embryo.

Sugiyama D, Arai K, Tsuji K.

Stem Cells Dev,2005 Dec,14(6):687-96

41 Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.

Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski ML, Suda T, Morishita K.

EMBO J,2005 Jun     ,24(11):1976-87

42 The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.

Lu X, Le Noble F, Yuan L, Jiang Q, De Lafarge B, Sugiyama D, Brテゥant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A.

Nature,2004 Nov, 432(7014):179-86

43 Human placenta-derived cells have mesenchymal stem/progenitor cell potential.

Fukuchi Y, Nakajima H, Sugiyama D, Hirose I, Kitamura T, Tsuji K.

Stem Cells,2004, 22(5):649-58

44 Erythropoiesis from acetyl LDL incorporating endothelial cells at the preliver stage.

Sugiyama D, Ogawa M, Hirose I, Jaffredo T, Arai K, Tsuji K.

Blood,2003 Jun,101(12):4733-8

45 Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors.

Hisakawa H, Sugiyama D, Nishijima I, Xu MJ, Wu H, Nakao K, Watanabe S, Katsuki M, Asano S, Arai K, Nakahata T, Tsuji K.

Blood,2001,Dec         98(13):3618-25

46 Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells.

Matsuoka S, Tsuji K, Hisakawa H, Xu Mj, Ebihara Y, Ishii T, Sugiyama D, Manabe A, Tanaka R, Ikeda Y, Asano S, Nakahata T.

Blood,2001 Jul ,98(1):6-12

47 CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages.

Matsuoka S, Ebihara Y, Xu M, Ishii T, Sugiyama D, Yoshino H, Ueda T, Manabe A, Tanaka R, Ikeda Y, Nakahata T, Tsuji K.

Blood,2001 Jan,97(2):419-25

 

(2)Case reports

1 Systemic plasmacytosis with deposition of interleukin (IL)-6 and elevated expression of IL-6 mRNA in the skin lesions.

Kanbe N, Kurosawa M, Akimoto S, Sugiyama D, Tamura J, Hirao Y, Miyachi Y.

Br J Dermatol,1998 Apr,138(4):721-3

 

(3)Review

(in English)

1 Molecular pathways governing development of vascular endothelial cells from ES/iPS cells.

Tan KS, Tamura K, Lai MI, Veerakumarasivam A, Nakanishi Y, Ogawa M, Sugiyama D.

Stem Cell Rev,2013 Oct,9(5):586-98

2 Mesodermal and hematopoietic differentiation from ES and iPS cells.

Inoue-Yokoo T, Tani K, Sugiyama D.

Stem Cell Rev,2013 Aug,9(4):422-34

3 Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells.

Lim WF, Inoue-Yokoo T, Tan KS, Lai MI, Sugiyama D.

Stem Cell Res Ther,2013 Jun,4(3):71

4 Zebrafish erythropoiesis and the utility of fish as models of anemia.

Kulkeaw K, Sugiyama D.

Stem Cell Res Ther,2012 Dec,3(6):55

5 Embryonic regulation of the mouse hematopoietic niche.

Sugiyama D, Inoue-Yokoo T, Fraser ST, Kulkeaw K, Mizuochi C, Horio Y.

ScientificWorldJournal,2011,11:1770-80

6 Definitive hematopoiesis from endothelial cells in the mouse embryo; a simple guide.

Sugiyama D, Tsuji K.

Trends Cardiovasc Med,2006 Feb,16(2):45-9

7 Tracing the hemangioblast during embryogenesis: developmental relationships between endothelial and hematopoietic cells.

Jaffredo T, Bollerot K, Sugiyama D, Gautier R, Drevon C.

Int J Dev Biol,2005,49(2-3):269-77

 

 (4)Book Chapters

1 Isolation of embryonic hematopoietic niche cells by flow cytometry and laser capture microdissection.

Sugiyama D, Sasaki T

Methods Mol Biol,2013,1035:57-65

2 Stem cell maintenance in embryos and adults.

Sugiyama D, Inoue T, Kulkeaw K.

Year Book of SCIENCE & TECHNOLOGY 2011 (McGRAW-HILL)             2011,258-261

 

(5) Symposium, Lecture, Conference

1 Identification of novel bioactive peptides regulating hematopoietic stem cells and study of its clinical application.

Sugiyama D

The 14th Congress of the Japanese Society for Regenerative Medicine

Oral presentation, March 19-21,2015,Yokoyhama,Japan

2 Embryonic regulation of the mouse hematopoietic niche.

Sugiyama D

NSW and ACTCell & Developmental Biology Meeting

Invited lecture, March 16,2015,Sydney,Australia

3 Embryonic hematopoietic stem/progenitors reside in muscle before bone

marrow hematopoiesis

D Sugiyama,T Inoue-Yokoo,C Yanagi-Mizuochi,K Kulkeaw,S Shirasawa,Y

Nakanishi,Y Tanaka

Keystone Symposia on molecular and cellular biology, Hematopoiesis

Oral and poster presentation, February 22-27,2015,Colorado,USA

4 Embryonic regulation of the mouse erythropoietic niche and implications for haematotherapy

Sugiyama D

The 76th Annual Meeting of the Japanese Society for Hematology

Oral presentation, January 16-18,2015,Kanazawa,Japan

5 Establishing ARO responsible for realizing creative next generation medicine

Sugiyama D

The 2nd Translational Research Symposium

Special lecture, March 3,2014,Fukuoka       Japan

6 Hepatoblasts comprise a niche for fetal liver hematopoiesis through extracellular matrix and cytokine production.

Sugiyama D, Kulkeaw K, Inoue T, Mizuochi C, Lim WF, Preedagasamzin S, Tan KS

Keystone Symposia on molecular and cellular biology, Hematopoiesis

Oral and poster presenttion, January 14-19,2013,Colorado,USA

7 Identification of novel bioactive substances through the analysis of hematopoietic niche regulation mechanisms during development.

Sugiyama D

The 17th Annual Meeting of The society of Biotherapeutic Approaches

Special Lecture, December 7,2013,Fukuoka,Japan

8 Hepatoblasts comprise a niche for fetal liver hematopoiesis through extracellular matrix and cytokine production.

Sugiyama D, Kulkeaw K, Inoue T, Lim WF, Preedagasamzin S, Tan KS

Cold Spring Harbor Asia Conferences,Stem Cells and Developmental Mechanisms

Oral presentation, December 3-7,2012,Suzhou       China

9 Embryonic regulation of the hematopoietic stem cell niche and implications for its expansion.

Sugiyama D

The 3rd Meeting of Asian Cellular Therapy Organization

Invited lecture, November 15‐17,2012       Chiangmai,Thailand

10 Embryonic regulation of the hematopoietic niche and implications for haematotherapy.

Sugiyama D

1st International Conference on Stem Cells

Invited lecture, September 6-11,2012,Chania,Greece

11 The use of animal models in hematopoiesis research

Sugiyama D

4th Malaysian Tissue Engineering & Regenerative Medicine Scientific Meeting

Invited lecture, June 3-4,2012,Langkawi,Malaysia

12 Haematopoietic development in mice and implications for haematotherapy

Sugiyama D

TESMA (Tissue Engineering & Regenerative Medicine Society of Malaysia) seminar

Invited lecture, December 19,2011,Kuala Lumpur,Malaysia

13 Hepatoblasts comprise a niche for fetal liver erythropoiesis through cytokine production.

Sugiyama D, Kulkeaw K, Mizuochi C, Horio Y, Okayama S, Inoue T

Cell Symposia (Stem Cell Programming & Reprogramming)

Oral and poster presentation, December 8-10,2011,Lisbon,Portugal

14 Haematopoietic development in mice and implications for haematotherapy.

Sugiyama D

The 3rd International Conference on Thalassemia in China

Invited lecture, November 4-6,2010,Nanning ,China

15 A role for hepatoblasts in the maintenance of fetal hematopoiesis.

Sugiyama D, Kulkeaw K, Mizuochi C, Horio Y

Keystone Symposia,Stem Cell Niche Interactions (D5)

Oral and poster presentation, April 21-26,2009,Whistler,Canada

16 Liver colonization from acetyl LDL incorporating endothelial cells in the mouse embryo.

Sugiyama D, Arai K, Tsuji K

British Society for Haematology 44th Annual Scientific Meeting

Oral and poster presentation, April,2004,Cardiff,UK

17 Liver colonization from endothelial cell-borne hematopoietic cells in the mouse embryo.

Sugiyama D, Arai K, Tsuji K

The 2003 Annual Meeting of the American Society of Hematology(the American Society of Hematology’s 45th Annual Meeting & Exposition)

Oral and poster presentation, December,2003,San Diego,USA

18 Erythropoiesis from Acetyl LDL incorporating endothelial cells at the pre-liver stage.

Sugiyama D, Arai K, Tsuji K   CDB symposium 2003

Oral and poster presemtation, March,2003,Kobe,Japan

19 Lymphoid Progenitors released from Endothelial Cells into Circulation in Mouse embryo.

Sugiyama D, Wang T, Takeshita A, Hirose I, Satoh M, Ito M, Kitamura T, Arai K, Tsuji K

EXPERIMENTAL BIOLOGY 2002 (FASEB Meeting)

Oral and poster presentation, Aplil,200,New Orleans,USA

20 Erythroid Progenitors are released to Circulation from Endothelial Cells in Mouse embryo.

Sugiyama D, Takeshita A, Nakahata T, Asano S, Tsuji K

The 2001 Annual Meeting of the American Society of Hematology(the American Society of Hematology’s 43rd Annual Meeting & Exposition)

Oral and poster presentation, December,2001,Orlando,USA

21 The analysis of early yolk sac hematopoiesis with whole embryo culture system.

Sugiyama D, Takeshita A, Nakahata T, Asano S, Tsuji K

ISEH 2001(International Society for Experimental Hematology 30th Annual Meeting)

Oral and poster presentation, August,2001,Tokyo,Japan

22 The analysis of early yolk sac hematopoiesis with whole embryo culture system.

Sugiyama D, Tsuji K   The 14th International Congress of Developmental Biology

Oral and poster presentation, July,2001,Kyoto,Japan

 

(6) Patents

1 Peptides inhibiting differentiation of hematopoietic stem cells or hematopoietic precursor cells and use thereof

PCT/JP2010/67011

Supported by Int’l patent application support system byJapan Science and Technology

Submitted on 2010/9/29

2 Novel use of acetyltransferase competitive inhibitory factor gm16515

PCT/JP2013/059744

Submitted on 2013/3/29

3 Biomarker for detecting factor for anemia in anemic patient

PCT/JP2013/072335

Supported by Int’l patent application support system byJapan Science and Technology

Submitted on  2013/8/21

4 Cyclin D1 gene expression inhibitor and anticancer drug

PCT/JP2014/054196

Supported by Int’l patent application support system byJapan Science and Technology

Submitted on 2014/2/21

5 Peptides expanding hematopoietic cells and use thereof

2014-070968

Submitted on 2014/3/31

 


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