Bridging the gap between academic discoveries and industrial applications requires a solid proof of concept as well as tailored de-risking strategies. In this pivotal but complex step, partnerships can be an effective answer in helping to determine whether a research asset can pave the way for new technological advances. In this endeavour, close interaction and dialogue between different communities – such as research, market players and investors – is crucial to reduce technology and market risk. This session will explore examples of partnerships that have successfully transformed early-stage innovations into tangible opportunities and pre-commercial phases. Why choose a collaborative model to secure go/no go stages for innovation? What are the determinants for an effective partnership?