SynAging focuses on disease-inducing misfolded protein aggregates. Advances in neurobiology helped to understand the pivotal role of soluble prion-like misfolded protein aggregates in neurodegenerative diseases. SynAging has proprietary procedures to create aggregates with highest reproducibility. Oligomers are used in vitro and in vivo to induce neurodegeneration acutely and provide drug developers with fast access to phenotypic models mimicking the corresponding neurodegenerative disease.