Financial considerations are often a major barrier to successful vaccine development, yet vaccination remains the most effective tools in the fight to help protect animals and livestock from countless new and emerging diseases. In the light of the COVID-19 pandemic, what are the innovative ways to address the challenge of preventing epidemics? How can One health concept contribute to deeper collaboration and pooled funding in vaccinology? What are the latest breakthrough technologies for future vaccine development? What is the role of diagnostic tools and what about their implementation?